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Celgene Corp, up 7 percent to $133.86, was amongthe top performers for both the S&P 500 and the Nasdaq 100 after the company said a late-stage trial of its cancerdrug Revlimid met the main goal of improving survival in newlydiagnosed blood cancer patients.

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Shares of companies like BioMarin Pharmaceutical Inc, Seattle Genetics Inc, Ariad PharmaceuticalsInc, Regeneron Pharmaceuticals Inc, VertexPharmaceuticals Inc and Clovis Oncology Inc have all rallied on news late last month that Onyx had spurnedAmgen's offer.

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